Post by kwombles on May 25, 2009 20:02:20 GMT -5
From a lovely person over at AoA:
KWombles
I went here
www.kwombles.com/psycunit2.html
to read your thoughts on autism- you said you are a parent to 3 children with autism and a psychology instructor-
"The Role of Theory of Mind in Autism Spectrum Disorder
by Kim Wombles (2007)
Some of the most beautiful people I have ever seen have been individuals with autism. They often
have this otherworldly look about them, as if they are not of this earth and are often deep in thought
of other places and other times. It is only with tremendous effort and great cost that they turn their
gaze outward and on others. It would be easy to dismiss this lack of awareness of others as extreme
narcissism, but it would be a colossal mistake. Individuals with autism can be extremely empathetic
when aware of another’s pain or discomfort; they will take on this pain as if it were their own. It is
not a lack of concern for others’ well-being that characterizes autism, but instead is a relative inability
to realize that other people can and are thinking, believing, and feeling different things from oneself.
Even when that awareness can be taught, there remains a disconnect between that knowledge and
the application of it to predict another’s behavior."
I am so sorry for your students as they are receiving a double dip of crap as you mix SB-C "theories" and your own personal opinion. These are not facts. Please add real research onto your list for students -- ie--
Neurotoxicology. 2009 May;30(3):331-7
Ockham's Razor and autism: the case for developmental neurotoxins contributing to a disease of neurodevelopment.
DeSoto MC.
Department of Psychology, University of Northern Iowa, Baker Hall, Cedar Falls, IA 50614-0505, United States. cathy.desoto@uni.edu
Much professional awareness regarding environmental triggers for ASD has been narrowly focused on a single possible exposure pathway (vaccines). Meanwhile, empirical support for environmental toxins as a broad class has been quietly accumulating. Recent research has shown that persons with ASD have comparatively higher levels of various toxins and are more likely to have reduced detoxifying ability, and, that rates of ASD may be higher in areas with greater pollution. This report documents that within the state with the highest rate of ASD, the rate is higher for schools near EPA Superfund sites, t (332)=3.84, p=.0001. The reasons for the rise in diagnoses likely involve genetically predisposed individuals being exposed to various environmental triggers at higher rates than in past generations.
Cell Biol Toxicol. 2009 Apr 9.
Induction of metallothionein in mouse cerebellum and cerebrum with low-dose thimerosal injection.
Minami T, Miyata E, Sakamoto Y, Yamazaki H, Ichida S.
Department of Life Sciences, School of Science & Engineering, Kinki University, 3-4-1 Kowakae, Higashi-osaka, Osaka, 577-8502, Japan, minamita@life.kindai.ac.jp.
Thimerosal, an ethyl mercury compound, is used worldwide as a vaccine preservative. We previously observed that the mercury concentration in mouse brains did not increase with the clinical dose of thimerosal injection, but the concentration increased in the brain after the injection of thimerosal with lipopolysaccharide, even if a low dose of thimerosal was administered. Thimerosal may penetrate the brain, but is undetectable when a clinical dose of thimerosal is injected; therefore, the induction of metallothionein (MT) messenger RNA (mRNA) and protein was observed in the cerebellum and cerebrum of mice after thimerosal injection, as MT is an inducible protein. MT-1 mRNA was expressed at 6 and 9 h in both the cerebrum and cerebellum, but MT-1 mRNA expression in the cerebellum was three times higher than that in the cerebrum after the injection of 12 microg/kg thimerosal. MT-2 mRNA was not expressed until 24 h in both organs. MT-3 mRNA was expressed in the cerebellum from 6 to 15 h after the injection, but not in the cerebrum until 24 h. MT-1 and MT-3 mRNAs were expressed in the cerebellum in a dose-dependent manner. Furthermore, MT-1 protein was detected from 6 to 72 h in the cerebellum after 12 microg/kg of thimerosal was injected and peaked at 10 h. MT-2 was detected in the cerebellum only at 10 h. In the cerebrum, little MT-1 protein was detected at 10 and 24 h, and there were no peaks of MT-2 protein in the cerebrum. In conclusion, MT-1 and MT-3 mRNAs but not MT-2 mRNA are easily expressed in the cerebellum rather than in the cerebrum by the injection of low-dose thimerosal. It is thought that the cerebellum is a sensitive organ against thimerosal. As a result of the present findings, in combination with the brain pathology observed in patients diagnosed with autism, the present study helps to support the possible biological plausibility for how low-dose exposure to mercury from thimerosal-containing vaccines may be associated with autism.
Curr Med Chem. 2009;16(2):157-70.
Immune-glutamatergic dysfunction as a central mechanism of the autism spectrum disorders.
Blaylock RL, Strunecka A.
Belhaven College, Jackson, Mississippi, USA.
Despite the great number of observations being made concerning cellular and the molecular dysfunctions associated with autism spectrum disorders (ASD), the basic central mechanism of these disorders has not been proposed in the major scientific literature. Our review brings evidence that most heterogeneous symptoms of ASD have a common set of events closely connected with dysregulation of glutamatergic neurotransmission in the brain with enhancement of excitatory receptor function by pro-inflammatory immune cytokines as the underlying mechanism. We suggest that environmental and dietary excitotoxins, mercury, fluoride, and aluminum can exacerbate the pathological and clinical problems by worsening excitotoxicity and by microglial priming. In addition, each has effects on cell signaling that can affect neurodevelopment and neuronal function. Our hypothesis opens the door to a number of new treatment modes, including the nutritional factors that naturally reduce excitotoxicity and brain inflammation.
Though most of the archaic psychology stuff you seem to post guarantees you a job in the psych dept- it has zero accountability in the definition and treatment of children with autism.
Posted by: Teresa Conrick | May 25, 2009 at 05:59 PM
www.ageofautism.com/2009/05/on-me....m.html#comments
KWombles
I went here
www.kwombles.com/psycunit2.html
to read your thoughts on autism- you said you are a parent to 3 children with autism and a psychology instructor-
"The Role of Theory of Mind in Autism Spectrum Disorder
by Kim Wombles (2007)
Some of the most beautiful people I have ever seen have been individuals with autism. They often
have this otherworldly look about them, as if they are not of this earth and are often deep in thought
of other places and other times. It is only with tremendous effort and great cost that they turn their
gaze outward and on others. It would be easy to dismiss this lack of awareness of others as extreme
narcissism, but it would be a colossal mistake. Individuals with autism can be extremely empathetic
when aware of another’s pain or discomfort; they will take on this pain as if it were their own. It is
not a lack of concern for others’ well-being that characterizes autism, but instead is a relative inability
to realize that other people can and are thinking, believing, and feeling different things from oneself.
Even when that awareness can be taught, there remains a disconnect between that knowledge and
the application of it to predict another’s behavior."
I am so sorry for your students as they are receiving a double dip of crap as you mix SB-C "theories" and your own personal opinion. These are not facts. Please add real research onto your list for students -- ie--
Neurotoxicology. 2009 May;30(3):331-7
Ockham's Razor and autism: the case for developmental neurotoxins contributing to a disease of neurodevelopment.
DeSoto MC.
Department of Psychology, University of Northern Iowa, Baker Hall, Cedar Falls, IA 50614-0505, United States. cathy.desoto@uni.edu
Much professional awareness regarding environmental triggers for ASD has been narrowly focused on a single possible exposure pathway (vaccines). Meanwhile, empirical support for environmental toxins as a broad class has been quietly accumulating. Recent research has shown that persons with ASD have comparatively higher levels of various toxins and are more likely to have reduced detoxifying ability, and, that rates of ASD may be higher in areas with greater pollution. This report documents that within the state with the highest rate of ASD, the rate is higher for schools near EPA Superfund sites, t (332)=3.84, p=.0001. The reasons for the rise in diagnoses likely involve genetically predisposed individuals being exposed to various environmental triggers at higher rates than in past generations.
Cell Biol Toxicol. 2009 Apr 9.
Induction of metallothionein in mouse cerebellum and cerebrum with low-dose thimerosal injection.
Minami T, Miyata E, Sakamoto Y, Yamazaki H, Ichida S.
Department of Life Sciences, School of Science & Engineering, Kinki University, 3-4-1 Kowakae, Higashi-osaka, Osaka, 577-8502, Japan, minamita@life.kindai.ac.jp.
Thimerosal, an ethyl mercury compound, is used worldwide as a vaccine preservative. We previously observed that the mercury concentration in mouse brains did not increase with the clinical dose of thimerosal injection, but the concentration increased in the brain after the injection of thimerosal with lipopolysaccharide, even if a low dose of thimerosal was administered. Thimerosal may penetrate the brain, but is undetectable when a clinical dose of thimerosal is injected; therefore, the induction of metallothionein (MT) messenger RNA (mRNA) and protein was observed in the cerebellum and cerebrum of mice after thimerosal injection, as MT is an inducible protein. MT-1 mRNA was expressed at 6 and 9 h in both the cerebrum and cerebellum, but MT-1 mRNA expression in the cerebellum was three times higher than that in the cerebrum after the injection of 12 microg/kg thimerosal. MT-2 mRNA was not expressed until 24 h in both organs. MT-3 mRNA was expressed in the cerebellum from 6 to 15 h after the injection, but not in the cerebrum until 24 h. MT-1 and MT-3 mRNAs were expressed in the cerebellum in a dose-dependent manner. Furthermore, MT-1 protein was detected from 6 to 72 h in the cerebellum after 12 microg/kg of thimerosal was injected and peaked at 10 h. MT-2 was detected in the cerebellum only at 10 h. In the cerebrum, little MT-1 protein was detected at 10 and 24 h, and there were no peaks of MT-2 protein in the cerebrum. In conclusion, MT-1 and MT-3 mRNAs but not MT-2 mRNA are easily expressed in the cerebellum rather than in the cerebrum by the injection of low-dose thimerosal. It is thought that the cerebellum is a sensitive organ against thimerosal. As a result of the present findings, in combination with the brain pathology observed in patients diagnosed with autism, the present study helps to support the possible biological plausibility for how low-dose exposure to mercury from thimerosal-containing vaccines may be associated with autism.
Curr Med Chem. 2009;16(2):157-70.
Immune-glutamatergic dysfunction as a central mechanism of the autism spectrum disorders.
Blaylock RL, Strunecka A.
Belhaven College, Jackson, Mississippi, USA.
Despite the great number of observations being made concerning cellular and the molecular dysfunctions associated with autism spectrum disorders (ASD), the basic central mechanism of these disorders has not been proposed in the major scientific literature. Our review brings evidence that most heterogeneous symptoms of ASD have a common set of events closely connected with dysregulation of glutamatergic neurotransmission in the brain with enhancement of excitatory receptor function by pro-inflammatory immune cytokines as the underlying mechanism. We suggest that environmental and dietary excitotoxins, mercury, fluoride, and aluminum can exacerbate the pathological and clinical problems by worsening excitotoxicity and by microglial priming. In addition, each has effects on cell signaling that can affect neurodevelopment and neuronal function. Our hypothesis opens the door to a number of new treatment modes, including the nutritional factors that naturally reduce excitotoxicity and brain inflammation.
Though most of the archaic psychology stuff you seem to post guarantees you a job in the psych dept- it has zero accountability in the definition and treatment of children with autism.
Posted by: Teresa Conrick | May 25, 2009 at 05:59 PM
www.ageofautism.com/2009/05/on-me....m.html#comments
